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Does prednisone, administered early in the course of ocular myasthenia, affect its progression to generalized disease?
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Barnett and Prineas describe the pathological and clinical findings in 12 patients with relapsing-remitting multiple sclerosis, who died shortly after the onset of a relapse.
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This paper reports the results of a prospective study of patients aged 50 years and older with acute isolated third, fourth, and sixth nerve palsies.
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Using data from the UK General Practice Research Database, Cleary and associates evaluated the hypothesis that late-onset (60-year-old subjects and older) seizures increase the risk of subsequent stroke.
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Among 56,250 British ICU patients, hospital mortality rates were higher among those admitted on the weekend or at night, but the differences disappeared when confounding by illness severity and other aspects of case mix were eliminated.
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Several factors are considered to be associated with the development of nosocomial infections in the ICU. Among them, indwelling devices that directly contact the blood and mucosal membrane such as the central venous catheter, urinary tract catheter and endotracheal tube are considered to be the most responsible risk factors in the development of nosocomial infections.
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Breast Cancer and the Use of Statins; Warnings Issued for IBS Drugs; FDA Actions
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Olesen and associates report on a phase II study of BIBN 4096 to evaluate the safety and efficacy of a first in class non-peptide, parenteral CGRP-receptor antagonist.
